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Monday, 13 February 2012

NKF-KDOQI Vascular Access Clinical Practice Guidelines


KF-KDOQI Vascular Access Guidelines – MCQ Set

1. According to KF-KDOQI guidelines, the preferred order for vascular access placement is:
A. Central venous catheter → AV graft → AV fistula
B. AV graft → AV fistula → Central venous catheter
C. AV fistula → AV graft → Central venous catheter
D. Central venous catheter → AV fistula → AV graft
➡️ Answer: C. AV fistula → AV graft → Central venous catheter


2. KF-KDOQI recommends AV fistula creation at least how many months before anticipated dialysis?
A. 1 month
B. 3 months
C. 6 months
D. 12 months
➡️ Answer: C. 6 months

3. What is the primary goal of vascular access according to KF-KDOQI?
A. Quick cannulation
B. Maximize catheter use
C. Provide reliable, long-term access with minimal complications
D. Avoid surgical procedures
➡️ Answer: C. Provide reliable, long-term access with minimal complications


4. According to KF-KDOQI, which site is NOT preferred for central venous catheter insertion?
A. Right internal jugular vein
B. Left subclavian vein
C. Right femoral vein
D. Left internal jugular vein
➡️ Answer: B. Left subclavian vein

(Due to high risk of central vein stenosis.)

5. KF-KDOQI recommends that a functional AV fistula should have all EXCEPT the following:
A. Palpable thrill
B. Flow rate >600 mL/min
C. Vein diameter ≥6 mm
D. Depth from skin ≤3 cm
➡️ Answer: B. Flow rate >600 mL/min

(Correct flow requirement is typically >600 mL/min, but the trick is that this may vary by setting; this is often cited with ultrasound flow thresholds.)


6. Which of the following statements is TRUE per KF-KDOQI guidelines on AV grafts?
A. Grafts should be used before fistulas due to ease of placement
B. Grafts are preferred over CVCs when fistulas are not possible
C. Grafts have lower infection rates than fistulas
D. Grafts can be used for dialysis immediately after surgery

➡️ Answer: B. Grafts are preferred over CVCs when fistulas are not possible

7. According to KF-KDOQI, the recommended surveillance method for detecting access dysfunction is:
A. Daily patient report only
B. Access flow monitoring and dynamic venous pressure
C. Annual Doppler ultrasound
D. Checking hemoglobin levels
➡️ Answer: B. Access flow monitoring and dynamic venous pressure


8. What is the recommended action if access flow is consistently <600 mL/min in a mature AV fistula?
A. Observe and recheck in 6 months
B. Continue using the access
C. Evaluate for stenosis or thrombosis
D. Stop dialysis

➡️ Answer: C. Evaluate for stenosis or thrombosis

9. Per KF-KDOQI, when is a tunneled cuffed catheter acceptable as permanent access?
A. Never
B. For patients with poor prognosis
C. For patients with acute kidney injury
D. For all patients waiting for fistula
➡️ Answer: B. For patients with poor prognosis

(e.g., limited life expectancy, unsuitable vessels for AV access)


10. KF-KDOQI recommends that AV fistula primary failure rates should be below:
A. 30%
B. 50%
C. 10%
D. 75%

➡️ Answer: A. 30%

11. According to KDOQI 2019/2020 updates, vascular access planning should be based on:
A. Age and gender
B. Predicted dialysis start date only
C. Individualized patient life plan and goals
D. Random access placement
➡️ Answer: C. Individualized patient life plan and goals


12. Which is NOT part of the “Rule of 6s” for AV fistula maturation per KDOQI?
A. Blood flow >600 mL/min
B. Vein depth <6 mm
C. Diameter >6 mm
D. Fistula usable after 6 days
➡️ Answer: D. Fistula usable after 6 days

(Correct: typically 6 weeks or more)

13. A patient’s AV fistula has no bruit or thrill. According to KDOQI, the next step is:
A. Start dialysis using it immediately
B. Cannulate deeper
C. Order Doppler ultrasound to assess patency
D. Wait a few days and reassess
➡️ Answer: C. Order Doppler ultrasound to assess patency


14. Which of the following is most associated with central venous stenosis, as per KDOQI?
A. Femoral vein use
B. Subclavian vein catheterization
C. Cephalic vein use
D. AV fistula in upper arm
➡️ Answer: B. Subclavian vein catheterization


15. The term "maturation failure" of an AV fistula is defined in KDOQI as failure to:
A. Be placed within 24 hours
B. Remain functional for 1 year
C. Cannulate successfully within 6 months
D. Be used successfully for dialysis within 6 weeks

➡️ Answer: D. Be used successfully for dialysis within 6 weeks

16. According to KDOQI, which of the following is NOT a recommended surveillance tool?
A. Physical examination
B. Access flow measurement
C. Static venous pressure
D. Monthly chest X-ray
➡️ Answer: D. Monthly chest X-ray


17. Which technique is recommended by KDOQI for reducing catheter-related bloodstream infections (CRBSIs)?
A. Use of chlorhexidine for site cleaning
B. Routine prophylactic antibiotics
C. Using bare hands during access
D. Changing dressings weekly

➡️ Answer: A. Use of chlorhexidine for site cleaning

18. Which access type has the lowest overall complication rate, per KDOQI?
A. Non-tunneled catheter
B. Tunneled catheter
C. AV graft
D. AV fistula
➡️ Answer: D. AV fistula


19. In terms of cannulation techniques, KDOQI recommends:
A. Buttonhole or rope-ladder over area technique
B. Area technique for beginners
C. Random puncture sites
D. Subcutaneous port over AV fistula

➡️ Answer: A. Buttonhole or rope-ladder over area technique

20. KDOQI 2020 encourages shared decision-making primarily to:
A. Reduce hospital length of stay
B. Improve dialysis machine settings
C. Ensure patient-centered vascular access planning
D. Encourage immediate catheter insertion

➡️ Answer: C. Ensure patient-centered vascular access planning 

Sunday, 5 February 2012

TYPE OF DIALYZER


Types of Dialyzers – MCQs


1. What is the primary function of a dialyzer in hemodialysis?
A. To filter waste products and excess fluid from the blood
B. To supply oxygen to the blood
C. To increase blood pressure
D. To administer medications
➡️ Answer: A. To filter waste products and excess fluid from the blood


2. Which material is commonly used in high-flux dialyzers?
A. Polysulfone
B. Polyethylene
C. Glass
D. Stainless steel
➡️ Answer: A. Polysulfone


3. What distinguishes a high-flux dialyzer from a low-flux dialyzer?
A. High-flux dialyzers have larger pore sizes allowing removal of larger molecules
B. Low-flux dialyzers have larger pores
C. High-flux dialyzers are smaller in size
D. Low-flux dialyzers filter faster
➡️ Answer: A. High-flux dialyzers have larger pore sizes allowing removal of larger molecules


4. Which dialyzer membrane type is considered most biocompatible?
A. Synthetic membranes like polysulfone and polyethersulfone
B. Cellulose membranes
C. Glass membranes
D. Rubber membranes
➡️ Answer: A. Synthetic membranes like polysulfone and polyethersulfone


5. What type of dialyzer membrane is made from modified cellulose?
A. Cellulose acetate
B. Polysulfone
C. Polycarbonate
D. Polyamide
➡️ Answer: A. Cellulose acetate


6. Which type of dialyzer membrane is more likely to activate complement and cause allergic reactions?
A. Cellulose-based membranes
B. Synthetic membranes
C. Polysulfone membranes
D. Polyethersulfone membranes
➡️ Answer: A. Cellulose-based membranes


7. What is the main advantage of high-flux dialyzers?
A. Better clearance of middle molecules and β2-microglobulin
B. Cheaper cost
C. Smaller size
D. Less protein loss
➡️ Answer: A. Better clearance of middle molecules and β2-microglobulin


8. Which of the following is NOT a typical dialyzer type?
A. Low-flux
B. High-flux
C. Medium cut-off (MCO)
D. Ultra-low flux
➡️ Answer: D. Ultra-low flux


9. What does the term “surface area” in dialyzers refer to?
A. The total area of the membrane available for diffusion
B. The size of the dialyzer casing
C. The size of blood tubing
D. The volume of dialysate used
➡️ Answer: A. The total area of the membrane available for diffusion


10. Which dialyzer membrane type is designed to allow removal of larger toxins while retaining essential proteins?
A. Medium cut-off (MCO) membranes
B. Low-flux membranes
C. Cellulose membranes
D. Polyamide membranes
➡️ Answer: A. Medium cut-off (MCO) membranes


11. What is a characteristic feature of low-flux dialyzers?
A. Smaller pores, primarily removing small molecules like urea
B. Large pores for middle molecule clearance
C. Synthetic membrane material only
D. High protein loss
➡️ Answer: A. Smaller pores, primarily removing small molecules like urea


12. Which dialyzer type is preferred for patients requiring removal of larger molecules such as β2-microglobulin?
A. High-flux dialyzer
B. Low-flux dialyzer
C. Cellulose dialyzer
D. No dialyzer needed
➡️ Answer: A. High-flux dialyzer


13. Which of the following materials is NOT commonly used for dialyzer membranes?
A. Polyvinyl chloride (PVC)
B. Polysulfone
C. Cellulose acetate
D. Polyethersulfone
➡️ Answer: A. Polyvinyl chloride (PVC)


14. What does the term “flux” refer to in dialyzers?
A. The rate of water permeability across the membrane
B. The blood flow rate
C. The dialysate flow rate
D. The dialyzer surface area
➡️ Answer: A. The rate of water permeability across the membrane


15. Which dialyzer membrane type tends to cause less activation of the immune system?
A. Synthetic membranes such as polysulfone
B. Cellulose membranes
C. Cotton membranes
D. Glass membranes
➡️ Answer: A. Synthetic membranes such as polysulfone


16. Which dialyzer type is generally associated with a lower risk of dialysis-related allergic reactions?
A. Synthetic membranes
B. Cellulose membranes
C. Both have equal risk
D. Neither causes allergic reactions
➡️ Answer: A. Synthetic membranes


17. What is a typical surface area range for adult dialyzers?
A. 1.0 to 2.5 square meters
B. 0.1 to 0.5 square meters
C. 5 to 10 square meters
D. 10 to 20 square meters
➡️ Answer: A. 1.0 to 2.5 square meters


18. What type of dialyzer would be best for a patient with amyloidosis due to dialysis?
A. High-flux dialyzer for β2-microglobulin removal
B. Low-flux dialyzer
C. Cellulose dialyzer
D. No dialyzer required
➡️ Answer: A. High-flux dialyzer for β2-microglobulin removal


19. Which dialyzer type requires the use of ultrapure dialysate to prevent complications?
A. High-flux dialyzer
B. Low-flux dialyzer
C. Cellulose dialyzer
D. All dialyzer types
➡️ Answer: A. High-flux dialyzer


20. Which of the following is true about medium cut-off (MCO) dialyzers?
A. They offer improved removal of middle molecules compared to traditional high-flux dialyzers
B. They have smaller pores than low-flux dialyzers
C. They are made of cellulose membranes
D. They are primarily used in peritoneal dialysis
➡️ Answer: A. They offer improved removal of middle molecules compared to traditional high-flux dialyzers


21. Which dialyzer type typically has a lower transmembrane pressure (TMP) requirement during dialysis?
A. Low-flux dialyzer
B. High-flux dialyzer
C. Medium cut-off dialyzer
D. Cellulose dialyzer
➡️ Answer: A. Low-flux dialyzer


22. What is one disadvantage of cellulose-based dialyzer membranes?
A. They have lower biocompatibility and may cause more complement activation
B. They are more expensive than synthetic membranes
C. They remove larger molecules better than synthetic membranes
D. They do not require rinsing before use
➡️ Answer: A. They have lower biocompatibility and may cause more complement activation


23. Which dialyzer membrane type is often preferred for patients with hypersensitivity reactions to dialysis membranes?
A. Synthetic membranes such as polysulfone
B. Cellulose membranes
C. Latex membranes
D. Rubber membranes
➡️ Answer: A. Synthetic membranes such as polysulfone


24. How does a larger surface area of a dialyzer membrane affect dialysis?
A. It increases solute clearance and improves dialysis efficiency
B. It decreases solute clearance
C. It increases risk of blood clotting
D. It has no effect on dialysis quality
➡️ Answer: A. It increases solute clearance and improves dialysis efficiency


25. Which of the following dialyzers has the highest permeability to water and solutes?
A. High-flux dialyzers
B. Low-flux dialyzers
C. Cellulose dialyzers
D. Polyamide dialyzers
➡️ Answer: A. High-flux dialyzers


26. What property of a dialyzer membrane affects the removal of middle molecules like β2-microglobulin?
A. Pore size
B. Membrane color
C. Dialysate temperature
D. Dialyzer casing material
➡️ Answer: A. Pore size


27. Which dialyzer membrane material is known for its excellent biocompatibility and mechanical strength?
A. Polysulfone
B. Cellulose
C. Rubber
D. Glass
➡️ Answer: A. Polysulfone


28. What is a key consideration when choosing a dialyzer for a patient?
A. The patient’s need for removal of small and middle molecules
B. The dialyzer’s color
C. The manufacturer’s brand only
D. The dialyzer size only
➡️ Answer: A. The patient’s need for removal of small and middle molecules


29. Which dialyzer type generally requires the use of ultrapure dialysate to prevent backfiltration complications?
A. High-flux dialyzers
B. Low-flux dialyzers
C. Cellulose dialyzers
D. Polyamide dialyzers
➡️ Answer: A. High-flux dialyzers


30. What is the main purpose of dialyzer rinsing before use?
A. To remove sterilant residues and prepare the membrane for dialysis
B. To increase dialyzer size
C. To clean blood tubing only
D. To cool the dialyzer
➡️ Answer: A. To remove sterilant residues and prepare the membrane for dialysis


31. Which dialyzer membrane type allows enhanced removal of protein-bound uremic toxins?
A. Medium cut-off (MCO) membranes
B. Low-flux membranes
C. Cellulose membranes
D. Polyamide membranes
➡️ Answer: A. Medium cut-off (MCO) membranes


32. Which of the following is true about dialyzer reuse?
A. Reuse requires strict protocols to ensure dialyzer function and patient safety
B. Dialyzers can be reused indefinitely without maintenance
C. Reuse is not allowed with synthetic membranes
D. Reuse decreases risk of infection
➡️ Answer: A. Reuse requires strict protocols to ensure dialyzer function and patient safety


33. Which factor does NOT affect dialyzer performance?
A. Blood flow rate
B. Membrane surface area
C. Dialysate composition
D. Patient's hair color
➡️ Answer: D. Patient's hair color


34. What is backfiltration in the context of dialyzers?
A. Movement of dialysate into the blood compartment due to pressure differences
B. Blood moving backward in the tubing
C. Air entering the dialyzer membrane
D. Dialysate leakage outside the machine
➡️ Answer: A. Movement of dialysate into the blood compartment due to pressure differences


35. Which dialyzer membrane type is typically sterilized using steam or gamma radiation?
A. Synthetic membranes such as polysulfone
B. Cellulose membranes only
C. Glass membranes
D. Plastic membranes only
➡️ Answer: A. Synthetic membranes such as polysulfone


36. Which dialyzer characteristic is important to minimize protein loss during dialysis?
A. Selective permeability
B. Color of dialyzer
C. Membrane thickness only
D. Tubing length
➡️ Answer: A. Selective permeability


37. What is the main benefit of synthetic membranes over cellulose membranes?
A. Improved biocompatibility and less complement activation
B. Cheaper cost
C. Easier to sterilize
D. No rinsing required
➡️ Answer: A. Improved biocompatibility and less complement activation


38. What parameter is often used to describe dialyzer efficiency?
A. Urea clearance rate
B. Dialysate temperature
C. Blood pressure
D. Patient weight
➡️ Answer: A. Urea clearance rate


39. What does the term “membrane permeability” refer to?
A. The ability of the dialyzer membrane to allow substances to pass through
B. The size of the dialyzer casing
C. The thickness of tubing
D. The dialysate flow rate
➡️ Answer: A. The ability of the dialyzer membrane to allow substances to pass through


40. Which dialyzer membrane type is preferred in patients with a history of dialysis-related allergic reactions?
A. Synthetic polysulfone membranes
B. Cellulose membranes
C. Rubber membranes
D. Plastic membranes
➡️ Answer: A. Synthetic polysulfone membranes


41. Which dialyzer type generally has the highest ultrafiltration coefficient (Kuf)?
A. High-flux dialyzers
B. Low-flux dialyzers
C. Cellulose dialyzers
D. Polyamide dialyzers
➡️ Answer: A. High-flux dialyzers


42. Which dialyzer membrane type is known for having a smooth surface that reduces clotting?
A. Polysulfone membranes
B. Cellulose membranes
C. Cotton membranes
D. Glass membranes
➡️ Answer: A. Polysulfone membranes


43. What is the typical sterilization method used for cellulose acetate dialyzers?
A. Gamma irradiation or ethylene oxide gas
B. Steam sterilization only
C. Dry heat only
D. No sterilization required
➡️ Answer: A. Gamma irradiation or ethylene oxide gas


44. What is the importance of dialyzer membrane thickness?
A. Thinner membranes generally allow better solute transfer
B. Thicker membranes improve blood flow
C. Thickness does not affect dialysis performance
D. Thicker membranes reduce cost
➡️ Answer: A. Thinner membranes generally allow better solute transfer


45. Which dialyzer type is preferred for high-efficiency hemodialysis?
A. High-flux dialyzer with large surface area
B. Low-flux dialyzer with small surface area
C. Cellulose dialyzer
D. Small surface area dialyzer
➡️ Answer: A. High-flux dialyzer with large surface area


46. What is the main function of the dialyzer housing?
A. To contain the blood and dialysate compartments and support the membrane
B. To sterilize the blood
C. To increase blood pressure
D. To monitor patient vital signs
➡️ Answer: A. To contain the blood and dialysate compartments and support the membrane


47. Which dialyzer membrane type is most prone to causing hypersensitivity reactions?
A. Unmodified cellulose membranes
B. Polysulfone membranes
C. Polyethersulfone membranes
D. Medium cut-off membranes
➡️ Answer: A. Unmodified cellulose membranes


48. What is the advantage of medium cut-off (MCO) membranes over traditional high-flux membranes?
A. Enhanced removal of larger middle molecules while retaining albumin
B. Reduced cost
C. Smaller pore size
D. Increased protein loss
➡️ Answer: A. Enhanced removal of larger middle molecules while retaining albumin


49. What is the main difference between hollow fiber and flat sheet dialyzers?
A. Hollow fiber dialyzers use numerous tiny tubes, while flat sheet dialyzers use flat membranes
B. Flat sheet dialyzers are more common in clinical practice
C. Hollow fiber dialyzers have less surface area
D. Flat sheet dialyzers are cheaper
➡️ Answer: A. Hollow fiber dialyzers use numerous tiny tubes, while flat sheet dialyzers use flat membranes


50. Which factor is NOT important when selecting a dialyzer for a patient?
A. Dialyzer membrane biocompatibility
B. Patient’s allergy history
C. Dialyzer color
D. Required solute clearance
➡️ Answer: C. Dialyzer color